Solving the mysteries of bioscience
Foundational Science Fuels Breakthroughs
Inspiring Next-Generation Scientists
Understanding human cells holistically and dynamically to predict and understand human health and disease.
Goals and Approach
Understanding how cells grow and develop, and being able to predict their future path, is essential for understanding human health.
Using advanced technologies to study the cell and its components as an integrated system, teams at the Allen Institute for Cell Science are working to understand a cell’s history and predict its future by looking at its present makeup and state. A deep holistic understanding of dynamic cellular behavior will ultimately help scientists better understand and predict disease.
In service of that aim, the Allen Institute for Cell Science generates fluorescently tagged human induced pluripotent stem cell lines connected to important cellular processes and makes these lines openly available to the scientific community. These teams also generate dynamic, high-resolution 3D images of live cells and develop predictive models and analysis tools that increase understanding of this vital building block of life.
Meet our advisors
Open science data, tools, and resources
The Allen Cell Explorer data portal offers an unprecedented view into the organizational diversity of human stem cells. Explore publicly available large-scale 3D imaging data, predictive models and cell observations, detailed methods, and descriptions of gene-edited cell lines available for research.
02.14.2024
06.05.2023
Nature Methods
Feb 01, 2024
Christopher Schmied, Michael S. Nelson, Sergiy Avilov, Gert-Jan Bakker, Cristina Bertocchi, Johanna Bischof, Ulrike Boehm, Jan Brocher, Mariana T. Carvalho, Catalin Chiritescu, Jana Christopher, Beth A. Cimini, Eduardo Conde-Sousa, Michael Ebner, Rupert Ecker, Kevin Eliceiri, Julia Fernandez-Rodriguez, Nathalie Gaudreault, Laurent Gelman, David Grunwald, Tingting Gu, Nadia Halidi, Mathias Hammer, Matthew Hartley, Marie Held, Florian Jug, Varun Kapoor, Ayse Aslihan Koksoy, Judith Lacoste, Sylvia Le Dévédec, Sylvie Le Guyader, Penghuan Liu, Gabriel G. Martins, Aastha Mathur, Kota Miura, Paula Montero Llopis, Roland Nitschke, Alison North, Adam C. Parslow, Alex Payne-Dwyer, Laure Plantard, Rizwan Ali, Britta Schroth-Diez, Lucas Schütz, Ryan T. Scott, Arne Seitz, Olaf Selchow, Ved P. Sharma, Martin Spitaler, Sathya Srinivasan, Caterina Strambio-De-Castillia, Douglas Taatjes, Christian Tischer, Helena Klara Jambor
Biophysical Journal
Sep 19, 2023
Graham T. Johnson, Eran Agmon, Matthew Akamatsu, Emma Lundberg, Blair Lyons, Wei Ouyang, Omar A. Quintero-Carmona, Megan Riel-Mehan, Susanne Rafelski, Rick Horwitz
Histochemistry and Cell Biology
Sep 01, 2023
Josh Moore, Daniela Basurto-Lozada, Sébastien Besson, John Bogovic, Jordão Bragantini, Eva M. Brown, Jean-Marie Burel, Xavier Casas Moreno, Gustavo de Medeiros, Erin E. Diel, David Gault, Satrajit S. Ghosh, Ilan Gold, Yaroslav O. Halchenko, Matthew Hartley, Dave Horsfall, Mark S. Keller, Mark Kittisopikul, Gabor Kovacs, Aybüke Küpcü Yoldaş, Koji Kyoda, Albane le Tournoulx de la Villegeorges, Tong Li, Prisca Liberali, Dominik Lindner, Melissa Linkert, Joel Lüthi, Jeremy Maitin-Shepard, Trevor Manz, Luca Marconato, Matthew McCormick, Merlin Lange, Khaled Mohamed, William Moore, Nils Norlin, Wei Ouyang, Bugra Özdemir, Giovanni Palla, Constantin Pape, Lucas Pelkmans, Tobias Pietzsch, Stephan Preibisch, Martin Prete, Norman Rzepka, Sameeul Samee, Nicholas Schaub, Hythem Sidky, Ahmet Can Solak, David R. Stirling, Jonathan Striebel, Christian Tischer, Daniel Toloudis, Isaac Virshup, Petr Walczysko, Alan M. Watson, Erin Weisbart, Frances Wong, Kevin A. Yamauchi, Omer Bayraktar, Beth A. Cimini, Nils Gehlenborg, Muzlifah Haniffa, Nathan Hotaling, Shuichi Onami, Loic A. Royer, Stephan Saalfeld, Oliver Stegle, Fabian J. Theis, Jason R. Swedlow
11.12.2024 - 11.15.2024
Learn more about our other Scientific Programs.
The Allen Institute for Brain Science is focused on understanding the complexities of the brain by mapping its cells and cell types with unprecedented precision and scale.
The Allen Institute for Immunology works to understand the delicate balancing act of the human immune system—how it works when we’re healthy, and what goes wrong in disease.