Annual Report | From Understanding to Impact

Billions of electrical pulses from 300,000 mouse neurons in action. A deep understanding of normal variability among genetically identical human cells. The brain equivalent of the Human Genome Project. Allen Institute researchers are tackling the next frontiers of science, bringing talented minds and teamwork to bear on large problems that require creative solutions.

View our 2022 highlights ►︎

Stories

Lab Notes | Cracking the code of addiction

Reward is essential for life, but these brain circuits are hijacked in drug addiction. Neuroscientists at the Allen Institute and the University of North Carolina are working to crack the biology of reward and addiction. Hear about their work and their hopes for the future of treating addiction in the latest episode of Lab Notes, a podcast from the Allen Institute.

Listen to the podcast ►︎

New Allen Distinguished Investigators announced

$10M in research funding will support eight cutting-edge projects in protein lifespan and nutrient sensing, led by 16 new Allen Distinguished Investigators.

Read more ►︎

How do human neurons respond to psychedelics?

Neuroscientists at the Allen Institute sent live human brain samples on a trip to glean insights into consciousness, therapy for depression and anxiety.

Read more ►︎

2022 Next Generation Leaders

Six early-career neuroscientists will help guide research into the complexities of the mammalian brain as part of the Next Generation Leaders program, a unique advisory panel for neuroscience at the Allen Institute.

Meet the Next Gen Leaders ►︎

New Resources & Events

New Alzheimer’s disease lesson plan

Lake Conferences in 2023

In the News

What Causes Alzheimer’s? Scientists Are Rethinking the Answer

Quanta Magazine, December 8, 2022

Patch-seq takes neuroscience to a multimodal place

Nature Methods, November 3, 2022

Of Mice and Men: How Paul Allen's Giving Set the Stage for an Ambitious Effort to Map the Human Brain

Inside Philanthropy, October 20, 2022

A Huge New Data Set Pushes the Limits of Neuroscience

WIRED, October 3, 2022